Search Flights from Guayaquil to Santiago

Quick Flight Summary from Guayaquil to Santiago

Key numbers to know before you book

  • Lowest recent price
    $297
  • Direct flight duration 4 hour 51 min
  • Arrival airports SCL
  • Best days to book Sunday, Wednesday
  • Average over the last 30 days
    $322

Cheapest flights from Guayaquil to Santiago

Best Price

Copa Airlines

Copa Airlines
23 Sep, Wed
Guayaquil – Santiago
1d 3h 54m
1 stop
GYESCL

Copa Airlines

Copa Airlines
27 Sep, Sun
Guayaquil – Santiago
1d 3h 54m
1 stop
GYESCL

LATAM Airlines

LATAM Airlines
24 Sep, Thu
Guayaquil – Santiago
6h 45m
1 stop
GYESCL
Cheapest Direct Flight

LATAM Airlines

LATAM Airlines
30 Sep, Wed
Guayaquil – Santiago
4h 51m
Non-stop
GYESCL

LATAM Airlines

LATAM Airlines
28 Sep, Mon
Guayaquil – Santiago
11h 55m
1 stop
GYESCL

LATAM Airlines

LATAM Airlines
1 Oct, Thu
Guayaquil – Santiago
10h 55m
1 stop
GYESCL

Avianca

Avianca
25 Sep, Fri
Guayaquil – Santiago
12h
1 stop
GYESCL

Avianca

Avianca
26 Sep, Sat
Guayaquil – Santiago
1d 3h 30m
1 stop
GYESCL

LATAM Airlines

LATAM Airlines
12 Oct, Mon
Guayaquil – Santiago
4h 51m
Non-stop
GYESCL

Last update: 22 September 2026 07:14

Estimated Prices for Guayaquil to Santiago Flights

Cheapest Day30 September Wednesday
Best Price
$289
Average Price
$293
$302
$289
22Tue
Sep
$290
23Wed
$302
24Thu
$293
25Fri
$294
26Sat
$290
27Sun
$290
28Mon
29Tue
$289
30Wed
$291
01Thu
Oct
02Fri
03Sat
04Sun
05Mon
06Tue
07Wed
08Thu
09Fri
10Sat
11Sun
12Mon
13Tue
14Wed
15Thu
16Fri
17Sat
18Sun
19Mon
20Tue
21Wed

Key Features of the Airlines

Information compiled by AI. For the most up-to-date information, contact the airline.

Transportation to Santiago City Center from Airport

Arturo Merino Benitez Intl. Airport

A Merino Benitez Airport connects Santiago, which hosts almost half of the Chilean population, with the world. The airport is meeting the transportation needs of its passengers with metro, taxi and rental vehicles.

Taxi

The taxis belonging to Euro Taxi and Radiotaxi companies, which are waiting for their passengers in the parking area in front of the terminal building of A Merino Benitez Airport, apply increased tariff on weekends and holidays. In addition, passengers who use a taxi from 10 pm to 7 am are required to pay a fee based on night tariff.

Metro

The metro which does not have a stop at the airport and the passengers who want to go to the city center can reach the Barrancas stop after an 8 minutes taxi journey and can go to the city center by metro from there. Metro, which makes its first ride at 05:40 in the morning, continues to carry passengers until 23:35 in the night. You can buy tickets sold at discounts on weekends. The passengers who want to go to the city center need to follow the Los Heroes stop and get off here.

Car Rental

Passengers who prefer a private rental car to reach the city center can rent a car from three car rental companies in the terminal building. While Europcar operates 24 hours a day, Sixt accepts passengers between 07:00 and 22:00 all week and Alamo between 06:30 and 23:00 all week.

Santiago Weather

5-Day Forecast • Min / Max Temperature

Monday
21 Sep
Cloudy
21°9°
Today
Tuesday
22 Sep
Cloudy
24°12°
Wednesday
23 Sep
Cloudy
21°14°
Thursday
24 Sep
Cloudy
20°12°
Friday
25 Sep
Cloudy
23°12°

More Information About Santiago

Frequently Asked Questions

When you search for Guayaquil-Santiago flights, Wingie directly gathers and compares instant data from all airlines. You can see all Guayaquil-Santiago flights together for the date you are looking for and choose the most suitable flight.
For Guayaquil-Santiago flights, you can use Jose Joaquin De Olmedo Intl. Airport as departure airport, and Arturo Merino Benitez Intl. Airport for arrival.
The flight distance between Guayaquil-Santiago is 3603 kilometers in total. The flight between the two cities takes 4 hour 30 minutes.
When the average prices are examined, the most suitable day for Guayaquil-Santiago flights is Monday.
On this route, low-cost airlines typically offer fares that include only cabin and hand baggage. Full-service airlines may include baggage and refreshment fees in the base price. The best option varies according to baggage needs. Based on current data, the lowest fare on this route with Copa Airlines starts from approximately $266.
AirlinePriceStandard inclusions
Copa Airlines
$266
1 piece X 10 kg cabin baggage (36x56x26 cm) / Paid Change
LATAM Airlines
$289
Paid Change (up to 48 hours) / No Refund
Avianca
$293
1 piece X 10 kg cabin baggage / No changes allowed / No Refund

Last update: 17.09.2026

Wingie App Banner
Get exclusive deals on the Wingie app!
Wingie QR Code
Scan the QR code to download the app for free
GooglePlay DownloadAppleStore Download